There a lots of different reasons why you might have pain in the joints, the most common ones being osteoarthritis, previous damage or fractures, and chronic low back pain, as well as all the other kinds of arthritis which cause similar symptoms of stiffness, pain, and restriction of movement.
Choosing your destination: There is some evidence that cold, wet weather makes joint inflammation worse and can cause more pain and stiffness. You may have noticed that your symptoms are worse before it rains, or in the winter. Warm, dry weather can ease the stiffness in the joints for some people.
What matters is how your joints respond to changes in weather. Consider the climate in your chosen destination, and the time of year you are planning to travel.
Where to stay: Consider how accessible you may need your accommodation to be. It is worth checking that there is a lift if you are not going to reliably manage the stairs. If you rely on a wheelchair, contact the accommodation directly to ensure that you will be able to get around comfortably.
Getting there: Allow yourself plenty of time to get to the airport, or if you are embarking on a long drive, schedule plenty of rest stops. Keeping your joints moving is very important to reduce stiffness.
When you arrive at the airport, make yourself known to the airline check in staff, and request assistance if you need it. This may involve reduced queueing time and help getting to the gate, as well as priority boarding and disembarking the aircraft.